Across every intervention and control group in three separate mouse studies, the estimated rate of vitality decline was consistently lower than the rate of survival decline; for example, female mice on 40% caloric restriction had a mean vitality-decline rate of 0.00011 compared to a survival-decline rate of 0.00079.
Sources
- Life-extending interventions do not necessarily result in ... - PMC (pmc.ncbi.nlm.nih.gov)
- https://link.springer.com/article/10.1007/s11357-025-01925-x (link.springer.com)
- https://mouseion.jax.org/stfb2026/74/ (mouseion.jax.org)
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