The reduction in amyloid deposits from estrogen skin patch use was most apparent among women carrying the APOE e4 genotype, a genetic variant associated with greater risk of late-onset Alzheimer's disease.
Sources
- Estrogen Patch in Newly Postmenopausal Women May Reduce ... (newsnetwork.mayoclinic.org)
- https://mayoclinic.elsevierpure.com/en/publications/early-postmenopausal-transdermal-17%CE%B2-estradiol-therapy-and-amyloi/ (mayoclinic.elsevierpure.com)
- https://www.upi.com/Health_News/2016/07/12/Estrogen-patch-may-reduce-postmenopausal-Alzheimers-risk-study-says/4671468353536 (upi.com)
- https://www.j-alz.com/content/estrogen-patch-newly-postmenopausal-women-may-reduce-alzheimer%E2%80%99s-risk (j-alz.com)
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